- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ANGPTL3 Antibody / Angiopoietin-like protein 3 (F49810)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F49810-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F49810-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | Q9Y5C1 |
| Applications | Western blot : 1:1000 |
| Limitations | This ANGPTL3 antibody is available for research use only. |
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ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Titration of the ANGPTL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 82-114 from the human protein was used as the immunogen for this ANGPTL3 antibody.
Aliquot the ANGPTL3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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