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Home >> Antibodies >> Angiotensin-converting enzyme 2 Antibody

Angiotensin-converting enzyme 2 Antibody (F49434)

  Catalog No Formulation Size Price (USD)  
Image F49434-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F49434-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of the Angiotensin-converting enzyme 2 antibody in K562 lysate. Predicted molecular weight: 90-100 kDa.
Western blot testing of Angiotensin-converting enzyme 2 antibody and 293 cell lysate. Predicted molecular weight: 90-100 kDa.
IHC analysis of FFPE human testis tissue stained with Angiotensin-converting enzyme 2 antibody
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q9BYF1
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
ELISA : peptide immunogen
Limitations This Angiotensin-converting enzyme 2 antibody is available for research use only.
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Description

ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator.

Application Notes

Titration of the Angiotensin-converting enzyme 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 773-805 from the human protein was used as the immunogen for this Angiotensin-converting enzyme 2 antibody.

Storage

Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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