- Tel: 858.663.9055
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- Tel: 858.663.9055
- Email: info@nsjbio.com
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ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator.
Titration of the Angiotensin-converting enzyme 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 773-805 from the human protein was used as the immunogen for this Angiotensin-converting enzyme 2 antibody.
Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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