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Home >> Antibodies >> Angiopoietin Antibody / ANGPT1

Angiopoietin Antibody / ANGPT1 (R32768)

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  Catalog No Formulation Size Price (USD)  
Image R32768 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human recombinant Angiopoietin protein (1ng/lane) with Angiopoietin antibody at 0.5ug/ml. Expected molecular weight: 57-75 kDa depending on glycosylation level.
Western blot testing of human recombinant Angiopoietin protein (1ng/lane) with Angiopoietin antibody at 0.5ug/ml. Expected molecular weight: 57-75 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt Q15389
Applications Western Blot : 0.5-1ug/ml
ELISA : 0.1-0.5ug/ml (human protein tested; request BSA-free format for coating)
Limitations This Angiopoietin antibody is available for research use only.
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Description

Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

Application Notes

Optimal dilution of the Angiopoietin antibody should be determined by the researcher.

Immunogen

Amino acids 204-241 (KHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRAT) from the human protein were used as the immunogen for the Angiopoietin antibody.

Storage

After reconstitution, the Angiopoietin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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