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- Email: info@nsjbio.com
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The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
The stated application concentrations are suggested starting points. Titration of the Angiopoietin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 404-432 from the human protein was used as the immunogen for the Angiopoietin 2 antibody.
Aliquot the Angiopoietin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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