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Home >> Antibodies >> Angiogenin Antibody

Angiogenin Antibody (R32581)

  Catalog No Formulation Size Price (USD)  
Image R32581 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 359
Western blot testing of human recombinant protein (1ng) using the Angiogenin antibody at 0.5ug/ml.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P03950
Applications Western blot : 0.5-1ug/ml
ELISA : 0.1-0.5ug/ml (human protein tested); request BSA-free format for coating
Limitations This Angiogenin antibody is available for research use only.
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Description

Angiogenin (ANG1), also known as Ribonuclease 5, is a small 123 amino acid protein that in humans is encoded by the ANG gene. The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

Application Notes

Optimal dilution of the Angiogenin antibody should be determined by the researcher.

Immunogen

A human recombinant protein corresponding to amino acids Q25-P147 was used as the immunogen for the Angiogenin antibody.

Storage

After reconstitution, the Angiogenin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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