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Home >> Antibodies >> Amyloid beta Antibody

Amyloid beta Antibody (F49577)

  Catalog No Formulation Size Price (USD)  
Image F49577-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F49577-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of Amyloid beta antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the APP gene (2). Predicted molecular weight 79~120kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Pig, Primate, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P05067
Applications Western blot : 1:1000
Limitations This Amyloid beta antibody is available for research use only.
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Description

APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Aβ is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimer's disease).[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Aβ can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]

Application Notes

Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 736-770 from the human protein was used as the immunogen for this Amyloid beta antibody.

Storage

Aliquot the Amyloid beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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