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Home >> Antibodies >> AMPK Antibody / PRKAA1

AMPK Antibody / PRKAA1 (F50188)

  Catalog No Formulation Size Price (USD)  
Image F50188-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F50188-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
AMPK antibody western blot analysis in SK-BR-3 lysate
Western blot analysis of AMPK antibody and mouse liver lysate
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q13131
Applications Western blot : 1:1000
Limitations This AMPK antibody is available for research use only.
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Description

AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha 1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.

Application Notes

Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 479-510 from the human protein was used as the immunogen for this AMPK antibody.

Storage

Aliquot the AMPK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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