- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
AMPK Antibody / PRKAA1 (F50188)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F50188-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F50188-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | Q13131 |
| Applications | Western blot : 1:1000 |
| Limitations | This AMPK antibody is available for research use only. |
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AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha 1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.
Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 479-510 from the human protein was used as the immunogen for this AMPK antibody.
Aliquot the AMPK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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