- Tel: 858.663.9055
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- Tel: 858.663.9055
- Email: info@nsjbio.com
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PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 474-502 from human PRKAA1 was used as the immunogen for this AMPK antibody.
Aliquot the AMPK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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