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Home >> Antibodies >> AMPK alpha Antibody / PRKAA1

AMPK alpha Antibody / PRKAA1 [clone 167CT22.1.6] (F40234)

  Catalog No Formulation Size Price (USD)  
Image F40234-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F40234-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
AMPK alpha antibody western blot analysis in K562 lysate.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, k
Clone Name 167CT22.1.6
Purity Purified
UniProt Q13131
Applications Western blot : 1:100-1:500
Limitations This AMPK alpha antibody is available for research use only.
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Description

AMPK alpha is the catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. [UniProt]

Application Notes

Titration of the AMPK alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This AMPK alpha antibody was produced from a mouse immunized with PRKAA1 recombinant protein.

Storage

Aliquot the AMPK alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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