- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
AMACR Antibody (F40477)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F40477-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F40477-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | Q9UHK6 |
| Applications | Western blot : 1:1000 IHC (Paraffin) : 1:50-1:100 Flow Cytometry : 1:10-1:50 Immunofluorescence : 1:10-1:50 |
| Limitations | This AMACR antibody is available for research use only. |
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This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Titration of the AMACR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 323-351 from the human protein was used as the immunogen for this AMACR antibody.
Aliquot the AMACR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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