- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Alpha Taxilin Antibody / TXLNA recognizes alpha taxilin (TXLNA), a ubiquitously expressed cytoplasmic protein that regulates intracellular vesicle trafficking through interactions with members of the syntaxin family of SNARE proteins. Alpha taxilin functions as an important adaptor during membrane fusion and vesicle transport, contributing to the precise delivery of proteins and lipids between intracellular compartments. By modulating syntaxin-dependent trafficking events, TXLNA supports normal secretory activity, membrane organization, and cellular homeostasis. Consequently, Alpha Taxilin Antibody / TXLNA is widely used to investigate membrane trafficking, exocytosis, and intracellular transport pathways.
TXLNA associates with multiple syntaxin isoforms involved in vesicle docking and fusion, allowing it to participate in diverse trafficking processes across many cell types. Through these interactions, alpha taxilin influences protein secretion, receptor recycling, membrane remodeling, and transport between the Golgi apparatus, endosomes, and plasma membrane. Because vesicle trafficking is fundamental to virtually every cell, TXLNA contributes to processes including cell growth, signal transduction, cell migration, and maintenance of tissue architecture.
Altered TXLNA expression has been reported in several malignancies and has been investigated for its potential roles in tumor progression, cellular proliferation, and metastatic behavior. In addition, disruption of vesicle trafficking pathways involving alpha taxilin may contribute to abnormalities in protein secretion and membrane dynamics associated with a variety of pathological conditions. As a result, TXLNA has become an informative marker for studies of membrane transport, intracellular signaling, cancer biology, and secretory pathway regulation.
NSJ Bioreagents' Alpha Taxilin Antibody / TXLNA supports investigations into vesicle trafficking, SNARE-mediated membrane fusion, protein secretion, intracellular transport, receptor recycling, and cancer biology. Reliable detection of TXLNA enables researchers to study an important regulator of syntaxin-dependent membrane trafficking and the cellular processes required for normal membrane organization and secretory function.
Explore additional antibodies involved in vesicle trafficking, membrane transport, and intracellular signaling on our Cell Biology Antibodies page.
Optimal dilution of the Alpha Taxilin antibody should be determined by the researcher.
E. coli-derived recombinant human protein (amino acids M1-A546) was used as the immunogen for the Alpha Taxilin antibody.
After reconstitution, the Alpha Taxilin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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