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Home >> Antibodies >> Alpha Lactalbumin Antibody / LALBA

Alpha Lactalbumin Antibody / LALBA (F54239)

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  Catalog No Formulation Size Price (USD)  
Image F54239-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54239-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC testing of FFPE human breast tissue with Alpha Lactalbumin antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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IHC testing of FFPE human breast tissue with Alpha Lactalbumin antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
IHC testing of FFPE human breast carcinoma tissue with Alpha Lactalbumin antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of human breast tissue lysate with Alpha Lactalbumin antibody. Predicted molecular weight ~16 kDa.
Western blot testing of human CEM cell lysate with Alpha Lactalbumin antibody. Predicted molecular weight ~16 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt P00709
Gene ID 3906
Applications Western blot : 1:1000-1:2000
Immunohistochemistry (FFPE) : 1:25-1:50
Limitations This Alpha Lactalbumin antibody is available for research use only.
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Description

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.

Application Notes

The stated application concentrations are suggested starting points. Titration of the Alpha Lactalbumin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 39-68 from the human protein were used as the immunogen for the Alpha Lactalbumin antibody.

Storage

Aliquot the Alpha Lactalbumin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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