Alpha-2M Antibody A2M/6556 / Pan-Proteinase Inhibitor Antibody [clone A2M/6556] (V4239)

Alpha-2M Antibody Protein Microarray Validation. Protein microarray analysis of Alpha-2M Antibody A2M/6556 / Pan-Proteinase Inhibitor Antibody using a HuProt array containing more than 19,000 full-length human proteins. A2M produces the dominant signal with a Z-score of approximately 34.9 and is clearly separated from the next-highest signal, resulting in an S-score of approximately 27.7. The Z-score represents signal strength relative to the array mean, while the S-score represents separation of the intended target from the next-highest signal. The strong target separation supports the specificity of this Alpha-2M Antibody.

Alpha-2M Antibody A2M/6556 Purity Analysis by SDS-PAGE. Electrophoretic analysis of purified, BSA-free Alpha-2M Antibody A2M/6556 / Pan-Proteinase Inhibitor Antibody with 2 ug loaded under non-reducing (NR) and reducing (R) conditions. The non-reduced sample shows predominantly intact antibody at approximately 150 kDa, while the reduced sample shows major bands at approximately 50 and 25 kDa corresponding to antibody heavy and light chains, respectively.

Alpha-2M Antibody in Human Hepatocellular Carcinoma IHC. Immunohistochemistry testing of Alpha-2M Antibody A2M/6556 / Pan-Proteinase Inhibitor Antibody in FFPE human hepatocellular carcinoma tissue. Heat-induced epitope retrieval was performed by boiling tissue sections in pH 9, 10 mM Tris with 1 mM EDTA for 20 min followed by cooling prior to staining. Widespread granular cytoplasmic immunoreactivity is observed throughout the tumor cells.