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- Email: info@nsjbio.com
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A2-Macroglobulin acts as an antiprotease and is able to inactivate an enormous variety of proteinases. It functions as an inhibitor of fibrinolysis by inhibiting plasmin and kallikrein. It functions as an inhibitor of coagulation by inhibiting thrombin. A2-macroglobulin may act as a carrier protein because it also binds to numerous growth factors and cytokines, such as platelet-derived growth factor, basic fibroblast growth factor, TGF-b, insulin, and IL-1b. [UniProt]
Optimal dilution of the Alpha-2-M antibody should be determined by the researcher.
A portin of amino acids 604-748 from the human protein was used as the immunogen for the Alpha-2-M antibody.
Aliquot the Alpha-2-M antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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