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Home >> Antibodies >> Alpha 1 Antitrypsin Antibody / SERPINA1 / AAT

Alpha 1 Antitrypsin Antibody / SERPINA1 / AAT [clone AOEF-19] (RQ4850)

  Catalog No Formulation Size Price (USD)  
Image RQ4850 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ug 359
Western blot testing of human fetal kidney lysate with Alpha 1 Antitrypsin antibody. Expected molecular weight: 47-52 kDa depending on the level of glycosylation.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AOEF-19
Purity Affinity purified
UniProt P01009
Applications Western blot : 1:500-1:2000
Limitations This Alpha 1 Antitrypsin antibody is available for research use only.
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Description

Alpha 1 Antitrypsin in an inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. [UniProt]

Application Notes

Optimal dilution of the Alpha 1 Antitrypsin antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human SERPINA1 / Alpha 1 Antitrypsin was used as the immunogen for the Alpha 1 Antitrypsin antibody.

Storage

Store the Alpha 1 Antitrypsin antibody at -20oC.

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