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It recognizes a protein of 54kDa, which is identified antitrypsin (AAT). The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.
Optimal dilution of the Alpha-1-Antitrypsin antibody should be determined by the researcher.
A recombinant human Alpha-1-Antitrypsin (AAT) protein fragment was used as the immunogen for the Alpha-1-Antitrypsin antibody.
Aliquot the Alpha-1-Antitrypsin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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