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Home >> Antibodies >> ALDH6A1 Antibody

ALDH6A1 Antibody [clone 147CT8.3.4] (F40222)

  Catalog No Formulation Size Price (USD)  
Image F40222-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F40222-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Fluorescent image of MCF-7 cells stained with ALDH6A1 antibody; Ab was diluted at 1:25 dilution. An Alexa Fluor 488 secondary Ab (green); DAPI counterstain (blue). Cytoplasmic actin was counterstained with Alexa Fluor 555 conjugated with Phalloidin (red).
Immunohistochemical analysis of paraffin-embedded human colon section using ALDH6A1 antibody at 1:25 dilution.
Western blot analysis of lysate from MCF-7, T47D cell line (left to right) using ALDH6A1 antibody at 1:1000 for each lane. Predicted molecular weight: ~58kDa.
Immunohistochemical analysis of paraffin-embedded human liver section using ALDH6A1 antibody at 1:25 dilution.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, k
Clone Name 147CT8.3.4
Purity Purified
UniProt Q02252
Applications Immunofluorescence : 1:25
IHC (Paraffin) : 1:25
Western blot : 1:1000
Limitations This ALDH6A1 antibody is available for research use only.
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Description

This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Application Notes

Titration of the ALDH6A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This ALDH6A1 antibody was produced from a mouse immunized with ALDH6A1 recombinant protein.

Storage

Aliquot the ALDH6A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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