ALDH2 Antibody / Mitochondrial Detoxification Enzyme Antibody [clone 5G7] (RQ5544)

ALDH2 Antibody Human A549 FACS. Flow cytometric analysis of ALDH2 expression was performed using ALDH2 antibody in human A549 cells. ALDH2, also known as Aldehyde Dehydrogenase 2, is a mitochondrial enzyme that catalyzes the detoxification of reactive aldehydes generated during alcohol metabolism, oxidative stress, and lipid peroxidation. Cells were blocked with goat sera and stained with ALDH2 antibody at 1 ug/million cells. Red = cells alone, Green = isotype control, Blue = ALDH2 antibody. A distinct rightward shift of the ALDH2 antibody histogram relative to the isotype control demonstrates specific detection of ALDH2 expression in A549 cells. These results support the utility of ALDH2 Antibody for studies of aldehyde metabolism, mitochondrial function, oxidative stress responses, and cellular detoxification pathways.

ALDH2 Antibody Human Cell Line Panel WB. Western blot analysis of ALDH2 expression was performed using anti-ALDH2 antibody in multiple human cell and tissue lysates. Lane 1: HepG2 lysate. Lane 2: placenta lysate. Lane 3: HEK293 lysate. Lane 4: SHG-44 lysate. Lane 5: THP-1 lysate. ALDH2, also known as Aldehyde Dehydrogenase 2, is a mitochondrial enzyme that detoxifies reactive aldehydes generated during alcohol metabolism, lipid peroxidation, and oxidative stress. A prominent immunoreactive band is detected at approximately 56 kDa in all samples, corresponding to the predicted molecular weight of ALDH2. The broad expression pattern observed across hepatic, placental, neuronal, and monocytic-derived samples is consistent with the widespread requirement for mitochondrial aldehyde detoxification and cellular protection from oxidative damage. These results support the utility of ALDH2 Antibody for studies of aldehyde metabolism, mitochondrial function, oxidative stress responses, and cellular detoxification pathways.

ALDH2 Antibody Rodent Tissue Panel WB. Western blot analysis of ALDH2 expression was performed using anti-ALDH2 antibody in rat and mouse tissue lysates. Lane 1: rat liver lysate. Lane 2: rat kidney lysate. Lane 3: rat heart lysate. Lane 4: mouse liver lysate. Lane 5: mouse kidney lysate. ALDH2, also known as Aldehyde Dehydrogenase 2, is a mitochondrial enzyme responsible for the oxidation and detoxification of reactive aldehydes generated during alcohol metabolism, lipid peroxidation, and oxidative stress. A prominent immunoreactive band is detected at approximately 56 kDa in all samples, corresponding to the predicted molecular weight of ALDH2. Strong expression across liver, kidney, and heart tissues is consistent with the essential role of ALDH2 in mitochondrial detoxification and metabolic homeostasis within highly active organs. These results support the utility of ALDH2 Antibody for studies of aldehyde metabolism, mitochondrial function, oxidative stress responses, and tissue protection mechanisms.

ALDH2 Antibody Human A431 IF. Immunofluorescent staining of FFPE human A431 cells with ALDH2 antibody revealed strong cytoplasmic staining with a finely granular distribution consistent with mitochondrial localization. ALDH2, also known as Aldehyde Dehydrogenase 2, is a mitochondrial detoxification enzyme that catalyzes the oxidation of reactive aldehydes generated during alcohol metabolism, lipid peroxidation, and oxidative stress. Green fluorescence indicates ALDH2 expression, while nuclei are counterstained with DAPI (blue). The predominantly cytoplasmic staining pattern is consistent with the known mitochondrial localization of ALDH2 and its essential role in maintaining cellular metabolic homeostasis and protection against aldehyde-induced damage. These results support the utility of ALDH2 Antibody for studies of aldehyde metabolism, mitochondrial function, oxidative stress responses, and cellular detoxification pathways.