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ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.
Optimal dilution of the Aldehyde Dehydrogenase 1A1 antibody should be determined by the researcher.
Recombinant full-length human ALDH1A1 protein was used as the immunogen for the Aldehyde Dehydrogenase 1A1 antibody.
Aliquot the Aldehyde Dehydrogenase 1A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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