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- Tel: 858.663.9055
- Email: info@nsjbio.com
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AKT2 is a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. AKT2 has been shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Titration of the AKT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 416-444 from the human protein was used as the immunogen for this AKT2 antibody.
Aliquot the AKT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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