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Home >> Antibodies >> AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95

AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95 [clone 29A07] (RQ8698)

  Catalog No Formulation Size Price (USD)  
Image RQ8698 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 439
Microvalidated Recrabbitmono
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Western blot testing of human HepG2 cell lysate with AKAP8 antibody. Predicted molecular weight ~76 kDa but routinely observed at ~95 kDa.
Availability 1-3 days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name 29A07
Purity Affinity chromatography
UniProt O43823
Applications Western blot : 1:500-1:2000
Limitations This AKAP8 antibody is available for research use only.
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Description

AKAP8 is an anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase. Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring. [UniProt]

Application Notes

Optimal dilution of the AKAP8 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human A-kinase anchor protein 8 was used as the immunogen for the AKAP8 antibody.

Storage

Store the AKAP8 antibody at -20oC.

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