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- Tel: 858.663.9055
- Email: info@nsjbio.com
A-kinase anchor protein 13 anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
Titration of the AKAP13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A partial recombinant protein corresponding to amino acids 18-170 from the human protein was used as the immunogen for the AKAP13 antibody.
Aliquot the AKAP13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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