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Home >> Antibodies >> AIFM1 Antibody / AIF / Apoptosis-Inducing Factor

AIFM1 Antibody / AIF / Apoptosis-Inducing Factor [clone GH-1] (RQ4816)

  Catalog No Formulation Size Price (USD)  
Image RQ4816 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ug 359
Western blot testing of human K562 cell lysate with AIFM1 antibody. Predicted molecular weight ~67 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name GH-1
Purity Affinity purified
UniProt O95831
Applications Western blot : 1:500-1:2000
Limitations This AIFM1 antibody is available for research use only.
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Description

'Apoptosis-inducing factor 1, mitochondrial' functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity.

Application Notes

Optimal dilution of the AIFM1 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human AIF / AIFM1 was used as the immunogen for the AIFM1 antibody.

Storage

Store the AIFM1 antibody at -20oC.

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