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Home >> Antibodies >> AIFM1 Antibody

AIFM1 Antibody (F54468)

  Catalog No Formulation Size Price (USD)  
Image F54468-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 359
Image
F54468-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 149
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt O95831
Applications Flow cytometry : 1:25 (1x10e6 cells)
Immunohistochemistry (FFPE) : 1:25
Western blot : 1:500-1:2000
Immunofluorescence : 1:25
Limitations This AIFM1 antibody is available for research use only.
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Description

AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.

Application Notes

The stated application concentrations are suggested starting points. Titration of the AIFM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 70-98 from the human protein were used as the immunogen for the AIFM1 antibody.

Storage

Aliquot the AIFM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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