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Home >> Antibodies >> AICDA Antibody [Discontinued, view alternative antibodies]

AICDA Antibody [Discontinued, view alternative antibodies] (RQ4010)

  Catalog No Formulation Size Price (USD)  
Image RQ4010 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
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Western blot testing of 1) rat spleen, 2) rat thymus, 3) mouse spleen and 4) mouse thymus lysate with AICDA antibody at 0.5ug/ml. Predicted molecular weight ~24 kDa.
Availability Discontinued
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q9GZX7
Applications Western Blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This AICDA antibody is available for research use only.
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    Reactivity : Human
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Description

Activation-induced cytidine deaminase, also known as AICDA and AID, is a 24 kDa enzyme which in humans is encoded by the AICDA gene. This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

Application Notes

Optimal dilution of the AICDA antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein corresponding to amino acids A91-T195 was used as the immunogen for the AICDA antibody.

Storage

After reconstitution, the AICDA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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