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Home >> Antibodies >> AICDA Antibody [Discontinued, view alternative antibodies]

AICDA Antibody [Discontinued, view alternative antibodies] (RQ4010)

  Catalog No Formulation Size Price (USD)  
Image RQ4010 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of 1) rat spleen, 2) rat thymus, 3) mouse spleen and 4) mouse thymus lysate with AICDA antibody at 0.5ug/ml. Predicted molecular weight ~24 kDa.
Availability Discontinued
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q9GZX7
Applications Western Blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This AICDA antibody is available for research use only.
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Description

Activation-induced cytidine deaminase, also known as AICDA and AID, is a 24 kDa enzyme which in humans is encoded by the AICDA gene. This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

Application Notes

Optimal dilution of the AICDA antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein corresponding to amino acids A91-T195 was used as the immunogen for the AICDA antibody.

Storage

After reconstitution, the AICDA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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