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Home >> Antibodies >> AFP Antibody / Alpha Fetoprotein

AFP Antibody / Alpha Fetoprotein [clone AAOO-1] (RQ5012)

  Catalog No Formulation Size Price (USD)  
Image RQ5012 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ug 359
Western blot testing of human HepG2 cell lysate with AFP antibody. Predicted molecular weight ~70 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AAOO-1
Purity Affinity purified
UniProt P02771
Applications Western blot : 1:500-1:2000
Limitations This AFP antibody is available for research use only.
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Description

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [RefSeq]

Application Notes

Optimal dilution of the AFP antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Alpha 1 Fetoprotein / AFP was used as the immunogen for the AFP antibody.

Storage

Store the AFP antibody at -20oC.

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