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Home >> Antibodies >> ADRBK2 Antibody / Beta-ARK-2 / GRK3

ADRBK2 Antibody / Beta-ARK-2 / GRK3 (RQ7080)

  Catalog No Formulation Size Price (USD)  
Image RQ7080 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 419
Western blot testing of 1) human HL60, 2) rat brain, 3) rat lung, 4) mouse brain and 5) mouse lung tissue lysate with ADRBK2 antibody. Expected molecular weight ~80 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P35626
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This ADRBK2 antibody is available for research use only.
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Description

Beta-adrenergic receptor kinase 2 (beta-ARK-2), also known as G-protein-coupled receptor kinase 3 (GRK3), is an enzyme that in humans is encoded by theADRBK2gene. The human ADRBK2 gene is located on 22q11. The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Application Notes

Optimal dilution of the ADRBK2 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids R591-L688) was used as the immunogen for the ADRBK2 antibody.

Storage

After reconstitution, the ADRBK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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