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Home >> Antibodies >> ADH4 Antibody / Alcohol dehydrogenase 4

ADH4 Antibody / Alcohol dehydrogenase 4 (R32498)

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Image R32498 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat liver, 2) mouse liver and 3) HepG2 lysate with ADH4 antibody at 0.5ug/ml. Predicted molecular weight ~40 kDa.
Western blot testing of 1) rat liver, 2) mouse liver and 3) HepG2 lysate with ADH4 antibody at 0.5ug/ml. Predicted molecular weight ~40 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P08319
Localization Cytoplasmic, membranous
Applications Western blot : 0.5-1ug/ml
Limitations This ADH4 antibody is available for research use only.
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Description

Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene. This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

Application Notes

Differences in protocols and secondary/substrate sensitivity may require the ADH4 antibody to be titrated for optimal performance.

Immunogen

Amino acids K218-F380 from the human protein were used as the immunogen for the ADH4 antibody.

Storage

After reconstitution, the ADH4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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