- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Adenine phosphoribosyltransferase Antibody / APRT (F54787)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54787-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54787-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | P07741 |
| Localization | Cytoplasmic, nuclear |
| Applications | Western blot : 1:500-1:1000 Immunofluorescence : 1:25 Flow cytometry : 1:25 (1x10e6 cells) Immunohistochemistry (FFPE) : 1:25 |
| Limitations | This Adenine phosphoribosyltransferase antibody is available for research use only. |
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A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
The stated application concentrations are suggested starting points. Titration of the Adenine phosphoribosyltransferase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 12-40 from the human protein was used as the immunogen for the Adenine phosphoribosyltransferase antibody.
Aliquot the Adenine phosphoribosyltransferase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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