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Home >> Antibodies >> ADAMTS2 Antibody

ADAMTS2 Antibody (R30533)

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  Catalog No Formulation Size Price (USD)  
Image R30533 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
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Western blot testing of ADAMTS2 antibody and rat samples: 1. brain; 2. heart tissue lysate
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Western blot testing of ADAMTS2 antibody and rat samples: 1. brain; 2. heart tissue lysate
IHC-P: ADAMTS2 antibody testing of rat heart tissue
IHC-F testing of ADAMTS2 antibody and rat heart tissue
IHC-F testing of rat trachea tissue
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt O95450
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
IHC (Frozen) : 0.5-1ug/ml
Limitations This ADAMTS2 antibody is available for research use only.
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Description

A Disintegrin And Metalloproteinase with ThromboSpondin motifs 2, also known as procollagen I N-proteinase (PC I-NP), is an enzyme that in humans is encoded by the ADAMTS2 gene. The gene contains 22 exons and is mapped to chromosome 5q23-q24 by analysis of somatic cell hybrids. ADAMTS2 is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary for collagen molecules to function normally and assemble into fibrils outside cells.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the ADAMTS2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human ADAMTS2 (KTRNQRIQELIDEMRK) was used as the immunogen for this ADAMTS2 antibody.

Storage

After reconstitution, the ADAMTS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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