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Home >> Antibodies >> ADAMTS1 Antibody

ADAMTS1 Antibody (R32796)

  Catalog No Formulation Size Price (USD)  
Image R32796 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of 1) rat brain and 2) mouse heart lysate with ADAMTS1 antibody at 0.5ug/ml. Predicted molecular weight: 84~120 kDa depending on glycosylation and processing.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt Q9UHI8
Applications Western Blot : 0.5-1ug/ml
Limitations This ADAMTS1 antibody is available for research use only.
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Description

A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Application Notes

Optimal dilution of the ADAMTS1 antibody should be determined by the researcher.

Immunogen

Amino acids 276-301 (SGLKHYLLTLFSVAARLYKHPSIRNS) from the human protein were used as the immunogen for the ADAMTS1 antibody.

Storage

After reconstitution, the ADAMTS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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