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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Actin Antibody MSA/8949R / Muscle Specific Actin Rabbit Monoclonal Antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).
For an alternative antibody recognizing muscle-specific actin isoforms, see our Muscle Actin Antibody HHF35, a mouse monoclonal antibody with extensive research use and validation by western blot and immunohistochemistry.
Optimal dilution of the Actin Antibody MSA/8949R / Muscle Specific Actin Rabbit Monoclonal Antibody should be determined by the researcher.
Recombinant human muscle actin protein was used as the immunogen for the Actin Antibody MSA/8949R.
Aliquot the Actin Antibody MSA/8949R and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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