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Home >> Antibodies >> ACO2 Antibody / Aconitase 2

ACO2 Antibody / Aconitase 2 (F50512)

  Catalog No Formulation Size Price (USD)  
Image F50512-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F50512-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with ACO2 antibody at 1:1000. Predicted molecular weight ~85 kDa.
Western blot analysis of ACO2 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the ACO2 gene (2). Predicted molecular weight ~85 kDa.
IHC analysis of FFPE human breast carcinoma tissue stained with ACO2 antibody
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q99798
Localization Cytoplasmic, granular
Applications Western blot : 1:500-1000
IHC (Paraffin) : 1:10-1:50
Limitations This ACO2 antibody is available for research use only.
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Description

Aconitase 2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Application Notes

Titration of the ACO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 294-325 from the human protein was used as the immunogen for this ACO2 antibody.

Storage

Aliquot the ACO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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