- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ACK1 Antibody / Activated CDC42 kinase 1 (F50698)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F50698-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F50698-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Predicted Reactivity | Bovine |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | Q07912 |
| Localization | Cytoplasmic |
| Applications | Western blot : 1:500-1000 IHC (Paraffin) : 1:50-1:100 |
| Limitations | This ACK1 antibody is available for research use only. |
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Activated CDC42 kinase 1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
Titration of the ACK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 934-964 from the human protein was used as the immunogen for this ACK1 antibody.
Aliquot the ACK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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