• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> ACK1 Antibody / Activated CDC42 kinase 1

ACK1 Antibody / Activated CDC42 kinase 1 (F50698)

  Catalog No Formulation Size Price (USD)  
Image F50698-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F50698-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot testing of human brain lysate with ACK1 antibody at 1:1000. Predicted molecular weight ~114 kDa.
IHC analysis of FFPE human hepatocarcinoma tissue stained with the ACK1 antibody
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Bovine
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q07912
Localization Cytoplasmic
Applications Western blot : 1:500-1000
IHC (Paraffin) : 1:50-1:100
Limitations This ACK1 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Description

Activated CDC42 kinase 1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.

Application Notes

Titration of the ACK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 934-964 from the human protein was used as the immunogen for this ACK1 antibody.

Storage

Aliquot the ACK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.