- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Acid Sphingomyelinase Antibody / SMPD1 (F54362)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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F54362-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54362-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity purified |
| UniProt | P17405 |
| Applications | Immunohistochemistry (FFPE) : 1:25 Western blot : 1:500-1:2000 Flow cytometry : 1:25 (1x10e6 cells) |
| Limitations | This Acid Sphingomyelinase antibody is available for research use only. |
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The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
The stated application concentrations are suggested starting points. Titration of the Acid Sphingomyelinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 391-419 from the human protein was used as the immunogen for the Acid Sphingomyelinase antibody.
Aliquot the Acid Sphingomyelinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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