Acid Phosphatase Antibody (Isoform 2 specific) (N1078)

Description

Acid phosphatases are a broad family of enzymes that differ widely in their amino acid length and homology, molecular weight and tissue of origin. They function to remove phosphate groups (or dephosphorylate) from proteins and perform best under acidic conditions. Disease states are sometimes characterized by abnormally high or low levels of Acid Phosphatase, leading to them being used as serological and histological disease markers. Prostatic Acid Phosphatase (PAP) was initially used as a prostate cancer marker but was later replaced with Prostate Serum Antigen (PSA), a more sensitive early stage cancer marker.

Application Notes

Provided assay concentrations are suggestions only, Acid Phosphatase antibody titration may be required for optimal results.

1. This antibody is specific to isoforms 2 (or B) and E of Acid Phosphatase.

Immunogen

The amino acid sequence used as immunogen for this antibody is specific to isoforms 2 (or B) and E of Acid Phosphatase.

Storage

Aliquot the Acid Phosphatase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Alternate Names

ACP1, Low molecular weight cytosolic acid phosphatase, Adipocyte acid phosphatase