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Home >> Antibodies >> Aciculin Antibody / PGM5

Aciculin Antibody / PGM5 [clone 14F8/F8] (V8411)

  Catalog No Formulation Size Price (USD)  
Image V8411-100UG 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 429
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V8411-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 199
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V8411SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 429
IHC staining of FFPE human uterus with Aciculin antibody (clone 14F8/F8). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human bladder with Aciculin antibody (clone 14F8/F8). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Aciculin antibody (clone 14F8/F8) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name 14F8/F8
Purity Protein G affinity chromatography
UniProt Q15124
Localization Cytoplasm
Applications Western blot : 1-2ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This Aciculin antibody is available for research use only.
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Description

Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.

Application Notes

Optimal dilution of the Aciculin antibody should be determined by the researcher.

Immunogen

The cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the Aciculin antibody.

Storage

Store the Aciculin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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