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Home >> Antibodies >> Acetyl-p53 Antibody (Lys370)

Acetyl-p53 Antibody (Lys370) [clone DEO-20] (RQ5059)

  Catalog No Formulation Size Price (USD)  
Image RQ5059 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of lysate from human HeLa cells treated with Trichostatin A, with acetyl-p53 antibody (Lys370). Predicted molecular weight ~53 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name DEO-20
Purity Affinity purified
UniProt P04637
Applications Western blot : 1:500-1:2000
Limitations This acetyl-p53 antibody (Lys370) is available for research use only.
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Description

Cellular tumor antigen p53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Acetylation of the protein influences its tumor suppressor function.[UniProt]

Application Notes

Optimal dilution of the acetyl-p53 antibody (Lys370) should be determined by the researcher.

Immunogen

A synthetic peptide specific to human p53 (surrounding acetylated K370) was used as the immunogen for the acetyl-p53 antibody (Lys370).

Storage

Store the acetyl-p53 antibody (Lys370) at -20oC.

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