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Home >> Antibodies >> ACE Antibody / Angiotensin-Converting Enzyme

ACE Antibody / Angiotensin-Converting Enzyme [clone ADCO-1] (RQ5388)

  Catalog No Formulation Size Price (USD)  
Image RQ5388 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ug 359
Western blot testing of human fetal kidney lysate with ACE antibody. Predicted molecular weight: 140-170 kDa.
Availability 1-2 weeks
Species Reactivity Human, Mouse
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name ADCO-1
Purity Affinity purified
UniProt P12821
Applications Western blot : 1:500-1:1000
Limitations This ACE antibody is available for research use only.
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Description

The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [RefSeq]

Application Notes

Optimal dilution of the ACE antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Angiotensin-Converting Enzyme was used as the immunogen for the ACE antibody.

Storage

Store the ACE antibody at -20oC.

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