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Home >> Antibodies >> ACE Antibody / Angiotensin I Converting Enzyme

ACE Antibody / Angiotensin I Converting Enzyme [clone ACE/7004R] (V9552)

  Catalog No Formulation Size Price (USD)  
Image V9552-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 499
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V9552-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 219
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V9552SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 499
SDS-PAGE analysis of purified, BSA-free ACE antibody (clone ACE/7004R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name ACE/7004R
Purity Protein A/G affinity
UniProt P12821
Localization Cell Surface
Applications ELISA (order BSA-free format for coating) :
Limitations This ACE antibody is available for research use only.
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Description

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Application Notes

Optimal dilution of the ACE antibody should be determined by the researcher.

Immunogen

A portion of amino acids 652-788 was used as the immunogen for the ACE antibody.

Storage

Aliquot the ACE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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