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Home >> Antibodies >> ACCN1 Antibody / ASIC2

ACCN1 Antibody / ASIC2 (F51596)

  Catalog No Formulation Size Price (USD)  
Image F51596-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F51596-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of ACCN1 antibody and human NCI-H460 lysate. Predicted molecular weight ~58 kDa.
IHC analysis of FFPE human brain tissue stained with ACCN1 antibody
ACCN1 antibody flow cytometric analysis (intracellular) of human WiDr cells (right histogram) compared to a negative control (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q16515
Localization Cytoplasmic
Applications Western blot : 1:500-1000
IHC (Paraffin) : 1:25-1:50
Flow Cytometry : 1:10-1:50
Limitations This ACCN1 antibody is available for research use only.
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Description

Amiloride-sensitive cation channel neuronal 1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN1 may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.

Application Notes

Titration of the ACCN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 120-148 from the human protein was used as the immunogen for this ACCN1 antibody.

Storage

Aliquot the ACCN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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