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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine (By similarity).
Titration of the ABHD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 98-127 from the human protein was used as the immunogen for this ABHD4 antibody.
Aliquot the ABHD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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