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Home >> Antibodies >> ABCG2 Antibody (BCRP)

ABCG2 Antibody (BCRP) (R30969)

  Catalog No Formulation Size Price (USD)  
Image R30969 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of ABCG2 antibody and Lane 1: rat liver; 2: rat spleen; 3: rat kidney; 4: mouse spleen tissue lysate. Predicted molecular weight ~72kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q7TMS5
Applications Western blot : 0.5-1ug/ml
Limitations This ABCG2 antibody is available for research use only.
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Description

ABCG2 (ATP-binding cassette, subfamily G, member 2) also known as ABCP, BCRP (Breast cancer resistance protein) or MRX (Mitoxantrone resistance-associated protein), is a protein that in humans is encoded by the ABCG2 gene. The gene encodes a membrane transporter belonging to the ATP-binding cassette (ABC) superfamily of membrane transporters, which are involved in the trafficking of biologic molecules across cell membranes.The protein is also a high capacity transporter for uric acid excretion in the kidney, liver, and gut. In vitro assays of isolated membrane preparations revealed a high-capacity, vanadate-sensitive ATPase activity associated with ABCG2 expression that was stimulated by compounds known to be transported by this protein.

Application Notes

Titration of the ABCG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids 152-167 (KNHEKNERINTIIKEL-mouse) were used as the immunogen for this BCRP / ABCG2 antibody.

Storage

The lyophilized ABCG2 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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