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- Tel: 858.663.9055
- Email: info@nsjbio.com
ATP-binding cassette sub-family C member 9 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.
Titration of the ABCC9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 640-669 from the human protein was used as the immunogen for this ABCC9 antibody.
Aliquot the ABCC9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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