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Home >> Antibodies >> ABCC11 Antibody

ABCC11 Antibody (F48871)

  Catalog No Formulation Size Price (USD)  
Image F48871-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F48871-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
ABCC11 antibody IHC analysis in formalin fixed and paraffin embedded breast carcinoma.
Western blot analysis of ABCC11 antibody and WiDr lysate. Predicted molecular weight: ~154/150kDa (isoforms 1/2).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q96J66
Localization Cytoplasmic, membranous
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This ABCC11 antibody is available for research use only.
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Description

ATP-binding cassette sub-family C member 11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.

Application Notes

Titration of the ABCC11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 343-372 from the human protein was used as the immunogen for this ABCC11 antibody.

Storage

Aliquot the ABCC11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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