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Home >> Antibodies >> ABCB7 Antibody

ABCB7 Antibody (F49439)

  Catalog No Formulation Size Price (USD)  
Image F49439-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F49439-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
IHC analysis of FFPE human hepatocarcinoma tissue stained with the ABCB7 antibody
ABCB7 antibody western blot analysis of Jurkat cell lysate
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O75027
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This ABCB7 antibody is available for research use only.
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Description

The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.

Application Notes

Titration of the ABCB7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 718-746 from the human protein was used as the immunogen for this ABCB7 antibody.

Storage

Aliquot the ABCB7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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