- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ABCB11 Antibody [Discontinued, view alternatives] (R30464)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R30464 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 299 |
| Availability | Discontinued |
| Species Reactivity | Human, Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| UniProt | O95342 |
| Applications | Western blot : 0.5-1ug/ml IHC (FFPE) : 0.5-1ug/ml |
| Limitations | This ABCB11 antibody is available for research use only. |
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Bile Salt Export Pump (BSEP) is a protein which in humans is encoded by the ABCB11 gene. It is a member of the superfamily of ATP-binding cassette (ABC) transporters. It is mapped to chromosome 2q24. The ABCB11 protein is mainly expressed in the liver. Mutation of the gene is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) which causes an increases the risk of hepatocellular carcinoma in early life.
The stated application concentrations are suggested starting amounts. Titration of the ABCB11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human ABCB11 (THEELMAQKGAYYKL) was used as the immunogen for this ABCB11 antibody.
After reconstitution, the ABCB11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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