AAMP Antibody / Angio associated migratory cell protein (R31545)

Description

Angio-associated migratory cell protein, or AAMP, is a multifunctional protein involved in angiogenesis, cell migration, and cytoskeletal organization. AAMP plays a key role in vascular development and endothelial cell function by regulating actin dynamics and cell adhesion. It is expressed in a variety of tissues, including the vasculature, and is particularly important in the context of tumor growth and metastasis due to its influence on endothelial cell motility and vascular remodeling.

AAMP exists in multiple isoforms resulting from alternative splicing. These isoforms may differ in tissue distribution, subcellular localization, or interaction with binding partners. The presence of distinct isoforms adds complexity to AAMP’s function, allowing it to participate in diverse signaling pathways depending on cellular context. Studying the expression patterns and regulation of these isoforms is important for understanding their individual roles in physiological and pathological conditions.

The use of an AAMP antibody enables researchers to detect and quantify AAMP protein across different biological samples. A high-quality AAMP antibody is essential for examining the expression of AAMP isoforms and for investigating their function in angiogenesis, inflammation, and cancer biology. Common applications include western blot, immunohistochemistry, immunofluorescence, and ELISA, where the AAMP antibody can provide reliable detection and localization of AAMP protein.

An AAMP antibody is a valuable tool for scientists studying vascular development, cancer progression, or cytoskeletal regulation, offering insight into the mechanisms by which AAMP contributes to endothelial cell behavior and tissue remodeling.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the AAMP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human partial recombinant protein (AA 235-434) was used as the immunogen for this AAMP antibody.

Storage

After reconstitution, the AAMP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.