- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Bleomycin hydrolase Antibody / BLMH (F54739)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54739-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
|
F54739-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | Q13867 |
| Localization | Cytoplasmic |
| Applications | Immunohistochemistry (FFPE) : 1:25 Western blot : 1:500-1:1000 |
| Limitations | This Bleomycin hydrolase antibody is available for research use only. |
|
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The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
The stated application concentrations are suggested starting points. Titration of the Bleomycin hydrolase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 212-242 from the human protein was used as the immunogen for the Bleomycin hydrolase antibody.
Aliquot the Bleomycin hydrolase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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