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Home >> Antibodies >> 17-beta-HSD 13 Antibody / HSD17B13

17-beta-HSD 13 Antibody / HSD17B13 [clone HSD17B13/13104] (V5741)

  Catalog No Formulation Size Price (USD)  
Image V5741-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5741-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5741SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human hepatocellular carcinoma tissue with 17-beta-HSD 13 antibody (clone HSD17B13/13104). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free 17-beta-HSD 13 antibody (clone HSD17B13/13104) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name HSD17B13/13104
Purity Protein G affinity
UniProt Q7Z5P4
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This 17-beta-HSD 13 antibody is available for research use only.
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Description

Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, 17-beta-HSD 13) is an enzyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

Application Notes

Optimal dilution of the 17-beta-HSD 13 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 1-200 of the human protein was used as the immunogen for the 17-beta-HSD 13 antibody.

Storage

Aliquot the 17-beta-HSD 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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